Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Selenium (as L-selenomethionine)
200 mcg
364%
Top Medical Research Studies
8
This study focused on how selenium-loaded porous silica nanospheres (Se@PSN) could help repair the heart following a myocardial infarction (MI). These tiny particles are designed to neutralize harmful molecules called reactive oxygen species, which play a significant role in heart damage during MI.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
Read More
9
Selenium nanoparticles aid heart recovery
Our exploration focused on the potential of selenium nanoparticles (SeNPs) to reduce damage from ischemia/reperfusion injury, a common aftermath of heart attacks. We found that these SeNPs, introduced through intravenous injection, demonstrated powerful antioxidant and anti-inflammatory effects.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
Read More
9
We explored the potential of selenium-doped copper formate (Cuf-Se) nanozymes in treating atherosclerosis, a key contributor to cardiovascular diseases. By targeting inflammation and oxidative stress, Cuf-Se shows promise by reducing reactive oxygen species and preventing the formation of foam cells.
Although this study primarily tests the effectiveness in mice, findings indicate a notable reduction in plaque formation and inflammation. Cuf-Se led to a five-fold decrease in plaque area, highlighting its potential as a novel treatment strategy for atherosclerosis.
Although this study primarily tests the effectiveness in mice, findings indicate a notable reduction in plaque formation and inflammation. Cuf-Se led to a five-fold decrease in plaque area, highlighting its potential as a novel treatment strategy for atherosclerosis.
Read More
Most Useful Reviews
9
Reduces thyroid antibodies
1 people found this helpful
I have been using this form of selenium for autoimmune thyroid disease for three years now, and it has significantly reduced my thyroid antibodies while improving my overall well-being. Truly excellent!
Read More
6
Important mineral benefits
62 people found this helpful
Selenium is a remarkable mineral in its best form and dosage. This yeastless selenium is crucial as it can be taken by those prone to candidal infections. The optimum dosage for preventing selenium deficiency is 200 mg daily; however, those with immunosuppression or heavy metal poisoning can take 400 mg safely. It must be taken with vitamin E since these antioxidants support each other. Selenium is irreplaceable in the fight against cancer and offers protection against cardiovascular disease and arterial conditions. Although relief from conditions may take 3-4 months, it is best taken alongside other vital antioxidants.
Read More
7.5
Thyroid support and more
9 people found this helpful
Selenium is an essential element for maintaining the normal functioning of the thyroid gland, aiding in the production of thyroid hormones. This mineral prevents cell destruction, reduces inflammation, and strengthens the immune system. People with Alzheimer's disease often have lower selenium levels. Moreover, selenium reduces the risk of cardiovascular disease by alleviating inflammation and oxidative stress. I take one tablet after breakfast, as advised by my gynaecologist.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8
- All Researches
9
Selenium nanoparticles aid heart recovery
Our exploration focused on the potential of selenium nanoparticles (SeNPs) to reduce damage from ischemia/reperfusion injury, a common aftermath of heart attacks. We found that these SeNPs, introduced through intravenous injection, demonstrated powerful antioxidant and anti-inflammatory effects.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
Read More
9
We explored the potential of selenium-doped copper formate (Cuf-Se) nanozymes in treating atherosclerosis, a key contributor to cardiovascular diseases. By targeting inflammation and oxidative stress, Cuf-Se shows promise by reducing reactive oxygen species and preventing the formation of foam cells.
Although this study primarily tests the effectiveness in mice, findings indicate a notable reduction in plaque formation and inflammation. Cuf-Se led to a five-fold decrease in plaque area, highlighting its potential as a novel treatment strategy for atherosclerosis.
Although this study primarily tests the effectiveness in mice, findings indicate a notable reduction in plaque formation and inflammation. Cuf-Se led to a five-fold decrease in plaque area, highlighting its potential as a novel treatment strategy for atherosclerosis.
Read More
8
Dietary antioxidants reduce mortality risk
We evaluated how dietary antioxidants, including vitamins like C and E, affect mortality risks in individuals with cardiovascular disease (CVD). Our analysis incorporated data from nearly 1,400 participants, using advanced statistical models to determine the connections between antioxidant intake and death rates.
The findings showed that higher levels of dietary antioxidants correlate with a lower risk of dying from CVD. Specifically, those in the highest antioxidant consumption group had significantly reduced mortality risks compared to those with lower intake. This points to the potential benefits of increasing antioxidants in the diet for better health outcomes in those managing CVD.
The findings showed that higher levels of dietary antioxidants correlate with a lower risk of dying from CVD. Specifically, those in the highest antioxidant consumption group had significantly reduced mortality risks compared to those with lower intake. This points to the potential benefits of increasing antioxidants in the diet for better health outcomes in those managing CVD.
Read More
8
This study focused on how selenium-loaded porous silica nanospheres (Se@PSN) could help repair the heart following a myocardial infarction (MI). These tiny particles are designed to neutralize harmful molecules called reactive oxygen species, which play a significant role in heart damage during MI.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
Read More
8
Selenium nanoparticles show heart benefits
We evaluated the use of selenium-quantum-dot-loaded silica nanoparticles as a new treatment for myocardial ischemia-reperfusion injury, a serious cardiovascular issue. These nanoparticles showed impressive abilities to scavenge harmful reactive oxygen species and improve heart cell function.
While traditional therapies struggle to target key problems like ferroptosis, the selenium nanoparticles effectively reduced this damage and preserved mitochondrial integrity. Our findings suggest that these nanoparticles could significantly lower heart damage and inflammation, bringing us closer to better treatment options for heart conditions.
While traditional therapies struggle to target key problems like ferroptosis, the selenium nanoparticles effectively reduced this damage and preserved mitochondrial integrity. Our findings suggest that these nanoparticles could significantly lower heart damage and inflammation, bringing us closer to better treatment options for heart conditions.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 7 Reviews
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduces thyroid antibodies
1 people found this helpful
I have been using this form of selenium for autoimmune thyroid disease for three years now, and it has significantly reduced my thyroid antibodies while improving my overall well-being. Truly excellent!
Read More
6
Important mineral benefits
62 people found this helpful
Selenium is a remarkable mineral in its best form and dosage. This yeastless selenium is crucial as it can be taken by those prone to candidal infections. The optimum dosage for preventing selenium deficiency is 200 mg daily; however, those with immunosuppression or heavy metal poisoning can take 400 mg safely. It must be taken with vitamin E since these antioxidants support each other. Selenium is irreplaceable in the fight against cancer and offers protection against cardiovascular disease and arterial conditions. Although relief from conditions may take 3-4 months, it is best taken alongside other vital antioxidants.
Read More
7.5
Thyroid support and more
9 people found this helpful
Selenium is an essential element for maintaining the normal functioning of the thyroid gland, aiding in the production of thyroid hormones. This mineral prevents cell destruction, reduces inflammation, and strengthens the immune system. People with Alzheimer's disease often have lower selenium levels. Moreover, selenium reduces the risk of cardiovascular disease by alleviating inflammation and oxidative stress. I take one tablet after breakfast, as advised by my gynaecologist.
Read More
6
Thyroid health enhancer
2 people found this helpful
Selenium is vital for maintaining normal thyroid function and helps improve hormone production. This microelement prevents cell destruction and inflammation while strengthening the immune system. Individuals with Alzheimer's often have reduced selenium levels in their blood. Selenium also lowers the risk of cardiovascular disease by combating inflammatory and oxidative stress. I take one tablet post-breakfast based on my gynaecologist's advice.
Read More
7.5
Supports cardiovascular health
Selenium is a potent antioxidant that prevents cell damage and bolsters immunity. It supports cardiovascular health while enhancing overall well-being.
Read More
Frequently Asked Questions
6
Important mineral benefits
62 people found this helpful
Selenium is a remarkable mineral in its best form and dosage. This yeastless selenium is crucial as it can be taken by those prone to candidal infections. The optimum dosage for preventing selenium deficiency is 200 mg daily; however, those with immunosuppression or heavy metal poisoning can take 400 mg safely. It must be taken with vitamin E since these antioxidants support each other. Selenium is irreplaceable in the fight against cancer and offers protection against cardiovascular disease and arterial conditions. Although relief from conditions may take 3-4 months, it is best taken alongside other vital antioxidants.
7.5
Supports cardiovascular health
Selenium is a potent antioxidant that prevents cell damage and bolsters immunity. It supports cardiovascular health while enhancing overall well-being.
9
Reduces thyroid antibodies
1 people found this helpful
I have been using this form of selenium for autoimmune thyroid disease for three years now, and it has significantly reduced my thyroid antibodies while improving my overall well-being. Truly excellent!
7.5
Family health boost
This selenium is fantastic! My whole family takes it as part of a course and we always keep it on hand for viral illnesses. At any sign of sickness, I quickly start taking selenium with vitamin C, and the ailment noticeably reduces. If my review is useful, please give it a thumbs up. Wishing you all good health!
7.5
Antioxidant action
Selenium is a powerful antioxidant essential for numerous bodily processes. It protects cell membranes and fats from peroxide radicals and hydrogen peroxide while safeguarding joints, the retina, and blood vessels. Together with vitamin E, it maintains cardiovascular system health and mitigates damage caused by heavy metals. Its primary function is its antioxidant action.
7.5
Thyroid support and more
9 people found this helpful
Selenium is an essential element for maintaining the normal functioning of the thyroid gland, aiding in the production of thyroid hormones. This mineral prevents cell destruction, reduces inflammation, and strengthens the immune system. People with Alzheimer's disease often have lower selenium levels. Moreover, selenium reduces the risk of cardiovascular disease by alleviating inflammation and oxidative stress. I take one tablet after breakfast, as advised by my gynaecologist.
6
Thyroid health enhancer
2 people found this helpful
Selenium is vital for maintaining normal thyroid function and helps improve hormone production. This microelement prevents cell destruction and inflammation while strengthening the immune system. Individuals with Alzheimer's often have reduced selenium levels in their blood. Selenium also lowers the risk of cardiovascular disease by combating inflammatory and oxidative stress. I take one tablet post-breakfast based on my gynaecologist's advice.
8
Dietary antioxidants reduce mortality risk
We evaluated how dietary antioxidants, including vitamins like C and E, affect mortality risks in individuals with cardiovascular disease (CVD). Our analysis incorporated data from nearly 1,400 participants, using advanced statistical models to determine the connections between antioxidant intake and death rates.
The findings showed that higher levels of dietary antioxidants correlate with a lower risk of dying from CVD. Specifically, those in the highest antioxidant consumption group had significantly reduced mortality risks compared to those with lower intake. This points to the potential benefits of increasing antioxidants in the diet for better health outcomes in those managing CVD.
The findings showed that higher levels of dietary antioxidants correlate with a lower risk of dying from CVD. Specifically, those in the highest antioxidant consumption group had significantly reduced mortality risks compared to those with lower intake. This points to the potential benefits of increasing antioxidants in the diet for better health outcomes in those managing CVD.
7
This population-based study involved over 16,000 adults with hypertension to explore how dietary antioxidants like selenium impact mortality rates. By tracking participants for nearly eight years, we discovered that those with the highest intake of antioxidants showed a significantly lower risk of dying from any cause or cardiovascular disease.
Specifically, selenium appeared beneficial, suggesting it might play a role in improving health outcomes for those with hypertension. However, further research, particularly randomized controlled trials, is essential to confirm these valuable insights.
Specifically, selenium appeared beneficial, suggesting it might play a role in improving health outcomes for those with hypertension. However, further research, particularly randomized controlled trials, is essential to confirm these valuable insights.
8
This study focused on how selenium-loaded porous silica nanospheres (Se@PSN) could help repair the heart following a myocardial infarction (MI). These tiny particles are designed to neutralize harmful molecules called reactive oxygen species, which play a significant role in heart damage during MI.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
We found that Se@PSN not only reduces cellular damage but also promotes the production of protective antioxidant proteins. By enhancing mitochondrial function, these nanospheres could potentially preserve heart function after an MI, demonstrating promising results for future treatments.
9
Selenium nanoparticles aid heart recovery
Our exploration focused on the potential of selenium nanoparticles (SeNPs) to reduce damage from ischemia/reperfusion injury, a common aftermath of heart attacks. We found that these SeNPs, introduced through intravenous injection, demonstrated powerful antioxidant and anti-inflammatory effects.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
By disrupting a harmful cellular cycle, they protected heart cells and minimized inflammation. In tests, SeNPs not only improved heart function but also decreased cell death and tissue scarring. These findings suggest that selenium nanoparticles could be a valuable addition to heart attack treatments.
References
- Hu X, Zhao Z, An Q, Li Y, Wang B. Association of independent dietary antioxidant intake, and CDAI level with risks of all-cause and cardiovascular-cause death among population with cardiovascular disease. BMC Public Health. 2025;25:1327. 10.1186/s12889-025-22481-1
- Li T, Liu X, Yang B, Wang Z, Chen Y, et al. Selenium-loaded porous silica nanospheres improve cardiac repair after myocardial infarction by enhancing antioxidant activity and mitophagy. Free Radic Biol Med. 2025;232:292. 10.1016/j.freeradbiomed.2025.03.004
- Li T, Yang B, Liu X, Shi D, Wang Z, et al. Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction. Int J Nanomedicine. 2025;20:1843. 10.2147/IJN.S500810
- Chen C, Ma J, Duan S, Xue M, Yang Z, et al. Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation. Biomaterials. 2025;318:123119. 10.1016/j.biomaterials.2025.123119
- Zhao S, Cao Y, Liu H, Liu A. Joint and independent associations of dietary antioxidant intakes with all-cause and cardiovascular mortality among patients with hypertension: a population-based cohort study. Nutr J. 2025;24:14. 10.1186/s12937-024-01062-9
- Huang X, Zhou Y, Guo Y, Yan D, Sun P, et al. Selenium-Doped Copper Formate Nanozymes with Antisenescence and Oxidative Stress Reduction for Atherosclerosis Treatment. Nano Lett. 2025;25:2662. 10.1021/acs.nanolett.4c05348
- Li B, Liu H, Mishra D, Yuan Z, Zhang Y, et al. The association between blood metals and cardiovascular diseases: findings from National Health and Nutrition Examination Survey 2011-2020. Front Cardiovasc Med. 2024;11:1479665. 10.3389/fcvm.2024.1479665
- Li X, Liu W, Jin T, Zhang T. Diet-derived circulating antioxidants and functional outcome after ischemic stroke: Evidence from genetic studies. J Stroke Cerebrovasc Dis. 2024;33:108039. 10.1016/j.jstrokecerebrovasdis.2024.108039
